The Best Hospitals Honor Roll highlights 20 hospitals that excel across most or all types of care evaluated by U.S. News. Hospitals received points if they were nationally ranked in the 16 specialties – the more specialties and the higher their rank, the more points they got – and if they were rated high performing in any of the 10 procedures and conditions. The top point-scorers made the Honor Roll.

- 1. Mayo Clinic, Rochester, Minnesota
- 2. Cleveland Clinic
- 3. Johns Hopkins Hospital, Baltimore
- 4 (tie). New York-Presbyterian Hospital-Columbia and Cornell, New York
- 4 (tie). UCLA Medical Center, Los Angeles
- 6. Massachusetts General Hospital, Boston
- 7. Cedars-Sinai Medical Center, Los Angeles
- 8. UCSF Medical Center, San Francisco
- 9. NYU Langone Hospitals, New York
- 10. Northwestern Memorial Hospital, Chicago
- 11. University of Michigan Hospitals-Michigan Medicine, Ann Arbor
- 12. Brigham and Women’s Hospital, Boston
- 13. Stanford Health Care-Stanford Hospital, Stanford, California
- 14. Mount Sinai Hospital, New York
- 15. Hospitals of the University of Pennsylvania-Penn Presbyterian, Philadelphia
- 16. Mayo Clinic-Phoenix
- 17. Rush University Medical Center, Chicago
- 18 (tie). Barnes-Jewish Hospital, St. Louis
- 18 (tie). Keck Hospital of USC, Los Angeles
- 20. Houston Methodist Hospital
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