Our 3D deep-learning system performed well in both primary and external validations, suggesting that it could potentially be used for automated detection of glaucomatous optic neuropathy based on SDOCT volumes. Screening with the deep-learning system is much faster than conventional glaucoma screening methods (ie, by experienced specialists), can be done automatically, and does not require a large number of trained personnel on site. Further prospective studies are warranted to estimate the incremental cost-effectiveness of incorporating this artificial intelligence-based model for screening for glaucoma, both in the general population and among at-risk people.
To read more: https://www.thelancet.com/journals/landig/article/PIIS2589-7500(19)30085-8/fulltext
I became engrossed in Mitchell’s drawings while browsing the book—they’re vivid, intimate—but her handwritten lyrics and poems are just as revelatory. It’s hard not to think about art-making of any kind as an alchemical process, in which feelings and experiences go in and something else comes out. Whatever happens in between is mysterious, if not sublime: suddenly, an ordinary sensation is made beautiful. Our most profound writers do this work with ease, or at least appear to. Mitchell’s lyrics are never overworked or self-conscious, and she manages to be precise in her descriptions while remaining ambiguous about what’s right and what’s wrong; in her songs, the cures and the diseases are sometimes indistinguishable. 
Joni Mitchell, in the foreword to “
Not until July 16 did Edison feel that he had a device worth patenting. The application he signed that day specified multiple timpani that “reproduced” vocal inflections and a sibilant-sensitive diaphragm. But a laboratory visitor (spying for Bell) found the instrument more powerful than clear, with the word schism sounding more like kim.
As part of the ANA Holdings exhibit, ANA is planning to unveil an all-new AVATAR robot “newme” 
FINICKY WESTERN EATERS would still be relieved to find filet mignon on the French menu of the hotel, now known as the Nikko Kanaya, a 90-minute drive from Tokyo. The dining room itself looks much as it did when it first opened, in 1893 and eagle-eyed diners might notice that the wooden pillars are decorated with flower carvings that echo those of the nearby Toshogu shrine. The views from the guest rooms are likewise unchanged—forest-covered mountains in the background, the same fastidiously manicured gardens in the foreground that the Einsteins strolled in 1922. Other parts of the hotel feel mildly haunted, like a Japanese version of “The Shining.” The wood-paneled lobby is well worn, stairwells creak noticeably and a shadowy cocktail bar features fading black-and-white photos of forgotten ’20s parties, with men in tuxedos and women in frocks smiling at the camera. 
Haus.me
Listen to the latest from the world of science, with Benjamin Thompson and Shamini Bundell. This week, investigating child mortality rates at a local level, and building genes from non-coding DNA.
Part of the luxury hotel chain Les Airelles, Le Grand Contrôle is named for the building it will occupy—a 17th-century structure once used as the finance hub of the palace. The hotel will have 14 rooms, some of them apartments, as well as a wellness center, indoor swimming pool, and an Alain Ducase restaurant.
